ANUA Niacinamide 10 TXA 4 Serum

ANUA Niacinamide 10 TXA 4 Serum

Brighter, more even skin — with four actives working at once. The ANUA Niacinamide 10 TXA 4 Serum from ANUA is a daily brightening serum formulated with 10% Niacinamide, 4% Tranexamic Acid (TXA), Dual Arbutin (Alpha-Arbutin + Arbutin), and a stable Vitamin C derivative — four brightening actives that each target a different stage of dark spot formation for compounded, visible results. A moisture and barrier complex of Polyglutamic Acid, 8 forms of Hyaluronic Acid, Ceramide NP, and Centella Asiatica keeps skin hydrated and comfortable throughout. The silk-water texture absorbs instantly — no stickiness, no residue.

Clinically shown to improve skin clarity and reduce the appearance of pigmentation in 2 weeks. Over 14,000 Amazon reviews. Fragrance-free, cruelty-free, vegan, paraben-free, silicone-free, alcohol-free — suitable for all skin types.

Size: 30ml / 1.01 fl. oz. (pink glass dropper bottle)

Clinical results

Visible improvement in skin clarity and reduction in pigmentation after 2 weeks of use. Clinical study conducted by the Korea Institute of Dermatological Sciences on 23 male and female participants (August 2023 – September 2024). Individual results may vary.

Key benefits

• Helps visibly improve the look of dark spots, post-acne marks, and uneven skin tone — four-active brightening system
• Skin clarity improvement confirmed in 2 weeks (clinical study, Korea Institute of Dermatological Sciences)
• Helps refine rough texture and enlarged pores — Niacinamide + gentle BHA
• Polyglutamic Acid + 8 forms of Hyaluronic Acid + Ceramide NP for lasting moisture and barrier support
• Lightweight watery texture — non-sticky, fast-absorbing, layers under moisturizer and makeup
• Fragrance-free, cruelty-free, vegan — suitable for all skin types including sensitive and acne-prone

How to use

After cleansing and toning, apply 2–3 drops from the dropper to the face and neck and gently pat until fully absorbed — do not rub. For targeted dark spots, apply an extra drop directly to those areas first. Follow with moisturizer. Always apply broad-spectrum SPF as the final morning step — the brightening actives in this serum increase sun sensitivity, and SPF is essential to protect your results. Can be used morning and evening. First-time users of 10% Niacinamide: start once daily and build to twice daily — some people experience temporary initial flushing at high Niacinamide concentrations.

Why we love it

Most brightening serums bet on one active ingredient. The ANUA Niacinamide 10 TXA 4 Serum uses four — and they work on four different stages of how dark spots form, so no part of the process is left unaddressed. Niacinamide blocks the final transfer of pigmentation into skin cells. Tranexamic Acid interrupts the chain reaction that triggers melanocytes to overproduce melanin in the first place — making it especially effective for melasma and post-inflammatory marks that keep coming back. Dual Arbutin (two forms for faster and longer-lasting effect) inhibits the enzyme that produces melanin at its source. And the stable Vitamin C derivative neutralizes the free radicals that prompt melanin production in response to UV and environmental stress, while also supporting collagen for a firmer-looking complexion. Four mechanisms, four actives, one serum — which is why results show up in two weeks rather than the months it takes with single-active treatments. The moisture complex underneath all of that is just as carefully considered: Polyglutamic Acid holds significantly more moisture than standard Hyaluronic Acid, 8 HA forms layer hydration at every skin depth, and Ceramide NP keeps the barrier strong so the brightening actives can work on healthy, supported skin. At BestSkincareUSA.com, the ANUA Niacinamide 10 TXA 4 Serum is our top brightening serum recommendation from ANUA for anyone dealing with dark spots, post-acne marks, or uneven skin tone.

Key ingredients

• 10% Niacinamide — A high-concentration dose of one of K-beauty's most trusted brightening, pore-refining, and barrier-supporting ingredients. At 10%, it visibly reduces the appearance of dark spots, minimizes pores, and improves overall skin texture with consistent use.
• 4% Tranexamic Acid (TXA) — Targets hyperpigmentation at the source by interrupting the signal that triggers melanocytes to overproduce melanin. Especially effective for melasma and post-inflammatory marks that tend to return even after surface treatment.
• Dual Arbutin (Alpha-Arbutin + Arbutin) — Two forms of Arbutin that inhibit the enzyme responsible for melanin production — one acting quickly, the other providing sustained, longer-lasting suppression for a more comprehensive brightening effect.
• Stable Vitamin C derivative (3-O-Ethyl Ascorbic Acid) — A stable, deeply penetrating form of Vitamin C that neutralizes the free radicals that prompt melanin production, while also supporting collagen and brightening from within. More stable and effective in a multi-active formula than pure Vitamin C.
• Polyglutamic Acid + 8 forms of Hyaluronic Acid + Ceramide NP — A comprehensive moisture and barrier complex that keeps skin deeply hydrated and barrier-intact throughout brightening treatment — so actives work on healthy, supported skin rather than a compromised surface.
• Centella Asiatica + Betaine Salicylate — Centella calms inflammation and supports skin recovery, especially useful for post-acne marks. Betaine Salicylate provides gentle exfoliation that helps all four brightening actives absorb more effectively.

Pro tips and pairings

Apply the ANUA Niacinamide 10 TXA 4 Serum to clean, slightly damp skin after toning for the best spread and absorption. Pat — don't rub. Morning SPF is essential: the four brightening actives all increase sun sensitivity, and skipping SPF will undo your results. For a complete ANUA brightening and hydration routine: cleanse with the ANUA Heartleaf Quercetinol Pore Deep Cleansing Foam, balance with the ANUA Birch Moisture Boosting Pad, apply this serum, then layer the ANUA Birch 70 Moisture Boosting Serum for hydration. Explore more from ANUA: Shop ANUA

About ANUA

ANUA is a South Korean skincare brand built on the belief that healthy skin comes from supporting the skin's natural balance through pure, organic ingredients, minimal irritation, and formulas that work with the skin rather than against it. Every ANUA formula prioritizes ingredient efficacy, environmental sustainability, and skin compatibility. 100% made in Korea.