MEDICUBE PDRN Lip Sleeping Mask

MEDICUBE PDRN Lip Sleeping Mask

Wake up to softer, smoother, and more nourished-looking lips with the MEDICUBE PDRN Lip Sleeping Mask. This intensive lip treatment delivers deep moisture with a candy-like glow finish that melts onto the lips without stickiness — helping improve the look of dryness, flakiness, and rough texture for lips that appear plump, supple, and visibly healthy overnight.

Formulated with Sodium DNA (Salmon PDRN), Hydrolyzed Collagen, Shea Butter (Butyrospermum Parkii), 5 peptides (Acetyl Tetrapeptide-5, Acetyl Hexapeptide-8, Carnosine, Palmitoyl Tripeptide-5, and Palmitoyl Tetrapeptide-7), Camellia Japonica Seed Oil, Camellia Japonica Flower Extract, Bisabolol, Adenosine, Yeast Beta-Glucan, and Tocopherol (Vitamin E), this is a comprehensive lip repair treatment in a comfortable balm format. Salmon PDRN supports lip barrier recovery and helps lips appear fuller and more bouncy. Hydrolyzed Collagen supports firmness and suppleness. Shea Butter delivers the rich moisture base. Five peptides activate collagen, elastin, and hyaluronic acid production for elasticity and density. Camellia Japonica Seed Oil soothes and softens. Adenosine and Yeast Beta-Glucan support lip vitality and comfort.

The MEDICUBE PDRN Lip Sleeping Mask works as both an overnight intensive treatment and a daily lip care product — versatile enough to replace a lip balm during the day and intensive enough to deliver visible repair results overnight. A great choice for anyone looking for a K-beauty lip sleeping mask, hydrating lip mask, or overnight lip treatment for dry and chapped lips. Vegan and dermatologically tested.

Size: 10g

Overview

The MEDICUBE PDRN Lip Sleeping Mask is a deeply moisturizing lip treatment created to care for dry, rough, and flaky lips while supporting a smoother, plumper-looking finish. Its melting balm texture glides on smoothly and settles into a non-sticky, candy-like gloss — comfortable enough for all-day wear and rich enough for intensive overnight lip repair. Clinically tested for both moisture and dead skin improvement from first use.

Clinical results

• Lip moisture improvement after one use — 40.3%
• Dead skin improvement after one use — 12.7%
• Dead skin improvement after 8 hours — 23.3%

Brand-reported results. Individual results may vary.

Key benefits

• Helps deeply moisturize dry and chapped lips — 40.3% moisture improvement after one use
• Supports softer, smoother-looking lips — 23.3% dead skin improvement after 8 hours
• Helps improve the look of flakiness and rough texture overnight
• Formulated with Salmon PDRN, Hydrolyzed Collagen, Shea Butter, and 5 peptides
• Non-sticky melting balm texture with a candy-like gloss finish
• Dual-use — daily lip care and overnight intensive treatment in one product

How to use

Daily lip care: Apply a light layer at any point during the day for all-day comfort and a candy-glow finish.
Overnight treatment: Apply generously as the last step of your evening skincare routine before bed. Let it work overnight and wipe off any excess in the morning.

Why we love it

Most lip masks trade off between effective and comfortable — thick enough to actually repair overnight usually means sticky and heavy enough to transfer onto your pillow. The MEDICUBE PDRN Lip Sleeping Mask uses a melting balm technology (built on Diisostearyl Malate and a dimer dilinoleate base) that gives the formula its unique behavior: it applies like a lip product, settles into a candy-glossy, non-sticky finish, and works all night without pillow transfer. The ingredient logic is also more sophisticated than most lip masks at this price point. Salmon PDRN — the same polydeoxyribonucleotide technology as in the MEDICUBE Salmon PDRN Pink Collagen Jelly Gel Mask — supports lip barrier recovery and helps lips appear fuller and more bouncy by stimulating the skin's natural repair processes. The five-peptide complex (Acetyl Tetrapeptide-5 for lip plumping, Acetyl Hexapeptide-8 for expression line relaxation, Carnosine for antioxidant and anti-glycation defense, Palmitoyl Tripeptide-5 for collagen stimulation, Palmitoyl Tetrapeptide-7 for elastin support) provides comprehensive structural support for the lip barrier. Camellia Japonica Seed Oil and Bisabolol add soothing and conditioning. And the 40.3% moisture improvement plus 23.3% dead skin improvement after 8 hours — confirmed clinically — is what makes this genuinely repairing rather than just glossy. At BestSkincareUSA.com, it's our top lip care recommendation from MEDICUBE for anyone who wants real overnight lip repair with a comfortable, non-disruptive finish.

Key ingredients deeper dive

• Sodium DNA (Salmon PDRN) — barrier recovery and plumping for the lip surface — The same polydeoxyribonucleotide technology used in the MEDICUBE Salmon PDRN Pink Collagen Jelly Gel Mask, now formulated for the lip area's more delicate, moisture-vulnerable skin. Salmon PDRN's DNA fragments — highly compatible with human skin cell DNA — support barrier recovery, stimulate the skin's natural repair and regeneration processes, and help the lips appear fuller and more bouncy by supporting the structural integrity of the lip tissue overnight in the MEDICUBE PDRN Lip Sleeping Mask.
• Shea Butter (Butyrospermum Parkii) and Hydrolyzed Collagen — deep moisture and firmness support — Shea Butter forms the rich, nourishing moisture base of the MEDICUBE PDRN Lip Sleeping Mask — high in oleic and stearic fatty acids, it deeply conditions the lip barrier and creates a weightless protective veil that prevents overnight moisture loss while you sleep. Hydrolyzed Collagen provides the firmness and suppleness support, helping the lips look and feel more resilient and structured in the morning.
• 5-peptide complex — comprehensive lip elasticity, plumping, and structural support — Acetyl Tetrapeptide-5 specifically supports lip plumping and reduces the appearance of lip lines; Acetyl Hexapeptide-8 (Argireline-class) relaxes the appearance of expression lines around the lip area; Carnosine provides antioxidant and anti-glycation defense for long-term lip skin health; Palmitoyl Tripeptide-5 signals collagen synthesis for structural support; Palmitoyl Tetrapeptide-7 supports elastin production for resilience. Together they address every dimension of lip aging and lip barrier strength across all Korean skincare routines targeting lip health.
• Camellia Japonica Seed Oil and Flower Extract — soothing, softening, and conditioning — Camellia Japonica (Japanese Camellia/Tsubaki) seed oil is one of the most revered traditional Japanese and Korean botanical oils — rich in oleic acid (85–90%) with natural slip and absorption properties that allow it to penetrate the lip barrier without heaviness. It soothes, softens, and nourishes the delicate skin of the lips while the Camellia Japonica Flower Extract provides complementary calming and antioxidant support alongside Bisabolol (a natural chamomile-derived soothing active) in the MEDICUBE PDRN Lip Sleeping Mask.
• Melting balm base (Diisostearyl Malate and dimer dilinoleate) — non-sticky candy glow without pillow transfer — The base of the MEDICUBE PDRN Lip Sleeping Mask uses emollient ester chemistry — Diisostearyl Malate and Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate — to achieve the melting balm behavior that gives the product its non-sticky, candy-glossy finish. These ingredients form a comfortable occlusive layer that locks in moisture and the active ingredients overnight without the tackiness or transfer of conventional petroleum-based lip masks, making it practical for all-day wear as well as overnight treatment.

Who it's for

The MEDICUBE PDRN Lip Sleeping Mask is designed for all lip types — particularly chronically dry, chapped, flaky, or thin-feeling lips that need intensive overnight repair. It's especially effective for those who want a single product that replaces both their daily lip balm and their weekly lip treatment, for those building a complete MEDICUBE lip care system alongside the MEDICUBE Salmon PDRN Pink Collagen Jelly Gel Mask for a PDRN-powered face and lip routine, and for anyone who has found conventional lip masks too sticky or heavy for nightly comfortable wear. Vegan — dermatologically tested.

Pro tips and pairings

For maximum overnight repair from the MEDICUBE PDRN Lip Sleeping Mask, apply after the rest of your skincare routine as the very last step — after moisturizer — so the balm layer seals in hydration on clean, well-prepared lip skin. Apply generously (more than you would a daytime lip balm) for the overnight intensive treatment; the formula is designed to absorb effectively throughout the night rather than all at once. In the morning, gently wipe off any remaining product and follow with a light reapplication before SPF. For the most complete MEDICUBE PDRN lip and face system, pair with the MEDICUBE Salmon PDRN Pink Collagen Jelly Gel Mask on the same evening — the gel mask handles the full face and the lip sleeping mask handles the lip zone for a comprehensive PDRN repair routine. Explore more from MEDICUBE: Shop MEDICUBE